Bio-Connect

FBXO22 antibody [N3C3]

GTX117774
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetFBXO22
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Overview

  • Supplier
    GeneTex
  • Product Name
    FBXO22 antibody [N3C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.29 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID26263
  • Target name
    FBXO22
  • Target description
    F-box protein 22
  • Target synonyms
    FBX22, FISTC1, TYMAS, F-box only protein 22, F-box protein FBX22p44, FIST domain containing 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ8NEZ5
  • Protein Name
    F-box only protein 22
  • Scientific Description
    This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Two transcript variants encoding different isoforms exist for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Simoneschi D, Rona G, Zhou N, et al. CRL4(AMBRA1) is a master regulator of D-type cyclins. Nature. 2021,592(7856):789-793. doi: 10.1038/s41586-021-03445-y
    Read this paper
  • Lignitto L, LeBoeuf SE, Homer H, et al. Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1. Cell. 2019,178(2):316-329.e18. doi: 10.1016/j.cell.2019.06.003
    Read this paper
  • Johmura Y, Maeda I, Suzuki N, et al. Fbxo22-mediated KDM4B degradation determines selective estrogen receptor modulator activity in breast cancer. J Clin Invest. 2018,128(12):5603-5619. doi: 10.1172/JCI121679
    Read this paper