Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA892132LA01HU at dilution of 1:100
FBXO3 Antibody
CSB-PA892132LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetFBXO3
Overview
- SupplierCusabio
- Product NameFBXO3 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID26273
- Target nameFBXO3
- Target descriptionF-box protein 3
- Target synonymsFBA; F-box only protein 3; F-box protein FBX3; FBX3
- HostRabbit
- IsotypeIgG
- Protein IDQ9UK99
- Protein NameF-box only protein 3
- Scientific DescriptionSubstrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203