FBXW2 antibody

GeneTex

FBXW2 antibody

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

FBXW2

F-box and WD repeat domain containing 2

F-box and WD-40 domain protein 2; F-box and WD-40 domain-containing protein 2; F-box/WD repeat-containing protein 2; FBW2; Fwd2; Md6

Rabbit

IgG

F-box/WD repeat-containing protein 2

F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats. [provided by RefSeq]

-20°C or -80°C,2°C to 8°C

12352203