FBXW2 blocking peptide

GeneTex

FBXW2 blocking peptide

9

Research Use Only

FBXW2

F-box and WD repeat domain containing 2

FBW2, Fwd2, Md6, F-box/WD repeat-containing protein 2, F-box and WD-40 domain protein 2, F-box and WD-40 domain-containing protein 2

F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

41116100

Human