Fc 11a-2 [960119-75-9]

MedChem Express

Fc 11a-2 [960119-75-9]

10

960119-75-9

Research Use Only

C16H16N2

236.31

Fc 11a-2, a benzimidazole compound, is an orally active and potent NLRP3 inflammasome inhibitor. Fc 11a-2 restrains the formation of NLRP3 inflammasome by inhibiting activation of caspase-1 and thus the activation of IL-1b/IL-18. Fc 11a-2 prevents the development of Dextran sulfate sodium (DSS; HY-116282C)-induced murine experimental colitis[1][2][3].

CC1=CC=C2N(CC)C(C3=CC=CC=C3)=NC2=C1

-20°C,2°C to 8°C

12352200