FACS analysis of CHO cells overexpressing human Fc epsilon R1 alpha protein using GTX00711 Fc epsilon R1 alpha antibody [CRA1].
![IHC-Fr analysis of Human atopic dermatis lesional skin tissue section using GTX00711 Fc epsilon R1 alpha antibody [CRA1]. Fixation : Aceton](https://www.genetex.com/upload/website/prouct_img/normal/GTX00711/GTX00711_20191104_IHC-Fr_w_23053121_789.webp "IHC-Fr analysis of Human atopic dermatis lesional skin tissue section using GTX00711 Fc epsilon R1 alpha antibody [CRA1]. Fixation : Aceton")
FACS analysis of CHO cells overexpressing human Fc epsilon R1 alpha protein using GTX00711 Fc epsilon R1 alpha antibody [CRA1].
Fc epsilon R1 alpha antibody [CRA1]
GTX00711
ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
TargetFCER1A
Overview
- SupplierGeneTex
- Product NameFc epsilon R1 alpha antibody [CRA1]
- Delivery Days Customer9
- Application Supplier NoteWB: ~1 microg/ml. IHC-P: ~1 microg/ml. IHC-Fr: ~1 microg/ml. FACS: 1-5 microg/ml - . Activation: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCRA1
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2205
- Target nameFCER1A
- Target descriptionFc epsilon receptor Ia
- Target synonymsFCE1A, FCERIA, FcERI, high affinity immunoglobulin epsilon receptor subunit alpha, Fc IgE receptor, alpha polypeptide, Fc epsilon RI alpha-chain, Fc fragment of IgE receptor Ia, Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide, Fc-epsilon RI-alpha, FcepsilonRI alpha chain, FcepsilonRIalpha, high affinity immunoglobulin epsilon receptor alpha-subunit, igE Fc receptor subunit alpha, immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide
- HostMouse
- IsotypeIgG2b
- Protein IDP12319
- Protein NameHigh affinity immunoglobulin epsilon receptor subunit alpha
- Scientific DescriptionThe immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Ito R, Takahashi T, Katano I, et al. Establishment of a human allergy model using human IL-3/GM-CSF-transgenic NOG mice. J Immunol. 2013,191(6):2890-9. doi: 10.4049/jimmunol.1203543Read this paper
- Ono HK, Nishizawa M, Yamamoto Y, et al. Submucosal mast cells in the gastrointestinal tract are a target of staphylococcal enterotoxin type A. FEMS Immunol Med Microbiol. 2012,64(3):392-402. doi: 10.1111/j.1574-695X.2011.00924.xRead this paper
- Takai T, Okumura K, Ra C. Direct expression of the extracellular portion of human FcepsilonRIalpha chain as inclusion bodies in Escherichia coli. Biosci Biotechnol Biochem. 2001,65(1):79-85.Read this paper
- Hasegawa S, Pawankar R, Suzuki K, et al. Functional expression of the high affinity receptor for IgE (FcepsilonRI) in human platelets and its' intracellular expression in human megakaryocytes. Blood. 1999,93(8):2543-51.Read this paper
- Suzuki K, Hirose T, Matsuda H, et al. The Fc receptor (FcR) gamma subunit is essential for IgE-binding activity of cell-surface expressed chimeric receptor molecules constructed from human high-affinity IgE receptor (Fc epsilon RI) alpha and FcR gamma subunits. Mol Immunol. 1998,35(5):259-70.Read this paper
Datasheet
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