FACS analysis of CHO cells overexpressing human Fc epsilon R1 alpha protein using GTX00711 Fc epsilon R1 alpha antibody [CRA1].
![IHC-Fr analysis of Human atopic dermatis lesional skin tissue section using GTX00711 Fc epsilon R1 alpha antibody [CRA1]. Fixation : Aceton](https://www.genetex.com/upload/website/prouct_img/normal/GTX00711/GTX00711_20191104_IHC-Fr_w_23053121_789.webp "IHC-Fr analysis of Human atopic dermatis lesional skin tissue section using GTX00711 Fc epsilon R1 alpha antibody [CRA1]. Fixation : Aceton")
FACS analysis of CHO cells overexpressing human Fc epsilon R1 alpha protein using GTX00711 Fc epsilon R1 alpha antibody [CRA1].
Fc epsilon R1 alpha antibody [CRA1] - Overexpression Validated
GTX00711
ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
ReactivityHuman
TargetFCER1A
Overview
- SupplierGeneTex
- Product NameFc epsilon R1 alpha antibody [CRA1] - Overexpression Validated
- Delivery Days Customer9
- ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCRA1
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2205
- Target nameFCER1A
- Target descriptionFc fragment of IgE receptor Ia
- Target synonymsFc epsilon receptor Ia; Fc epsilon RI alpha-chain; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc IgE receptor, alpha polypeptide; FCE1A; Fc-epsilon RI-alpha; FcERI; high affinity immunoglobulin epsilon receptor alpha-subunit; high affinity immunoglobulin epsilon receptor subunit alpha; igE Fc receptor subunit alpha; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide
- HostMouse
- IsotypeIgG2b
- Scientific DescriptionThe immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Establishment of a human allergy model using human IL-3/GM-CSF-transgenic NOG mice. Ito R et al., 2013 Sep 15, J ImmunolRead more
- Submucosal mast cells in the gastrointestinal tract are a target of staphylococcal enterotoxin type A. Ono HK et al., 2012 Apr, FEMS Immunol Med MicrobiolRead more
- Direct expression of the extracellular portion of human FcepsilonRIalpha chain as inclusion bodies in Escherichia coli. Takai T et al., 2001 Jan, Biosci Biotechnol BiochemRead more
- Functional expression of the high affinity receptor for IgE (FcepsilonRI) in human platelets and its intracellular expression in human megakaryocytes. Hasegawa S et al., 1999 Apr 15, BloodRead more
- The Fc receptor (FcR) gamma subunit is essential for IgE-binding activity of cell-surface expressed chimeric receptor molecules constructed from human high-affinity IgE receptor (Fc epsilon RI) alpha and FcR gamma subunits. Suzuki K et al., 1998 Apr, Mol ImmunolRead more