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Fc epsilon R1 alpha antibody [MAR-1]

Research Use Only
GTX01480
GeneTex
ApplicationsFlow Cytometry, Other Application
Product group Antibodies
ReactivityMouse
TargetFCER1A
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    Fc epsilon R1 alpha antibody [MAR-1]
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    MAR-1
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2205
  • Target name
    FCER1A
  • Target description
    Fc fragment of IgE receptor Ia
  • Target synonyms
    Fc epsilon receptor Ia; Fc epsilon RI alpha-chain; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc IgE receptor, alpha polypeptide; FCE1A; Fc-epsilon RI-alpha; FcERI; high affinity immunoglobulin epsilon receptor alpha-subunit; high affinity immunoglobulin epsilon receptor subunit alpha; igE Fc receptor subunit alpha; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide
  • Host
    Hamster
  • Isotype
    IgG
  • Scientific Description
    The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011]
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Type 2 innate immunity in helminth infection is induced redundantly and acts autonomously following CD11c(+) cell depletion. Smith KA et al., 2012 Oct, Infect Immun
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  • Critical role of P1-Runx1 in mouse basophil development. Mukai K et al., 2012 Jul 5, Blood
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  • Chronic helminth infection reduces basophil responsiveness in an IL-10-dependent manner. Larson D et al., 2012 May 1, J Immunol
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