ProductsBack/Fc gamma RIIB/CD32b, Cynomolgus (Biotinylated, HEK293, His-Avi)

Fc gamma RIIB/CD32b, Cynomolgus (Biotinylated, HEK293, His-Avi)

Name: Fc gamma RIIB/CD32b, Cynomolgus (Biotinylated, HEK293, His-Avi)
SKU: HY-P76799_M09
Availability: BackOrder

HY-P76799

Protein IDQ8SPW3

Product group Proteins / Signaling Molecules

Overview

Supplier
MedChem Express
Product Name
Fc gamma RIIB/CD32b, Cynomolgus (Biotinylated, HEK293, His-Avi)
Delivery Days Customer
10
Certification
Research Use Only
Gene ID102139530
Target name
FCGR2B
Target description
Fc gamma receptor IIb
Target synonyms
FCGR, low affinity immunoglobulin gamma Fc region receptor II-b, Fc fragment of IgG receptor IIb, Fc fragment of IgG, low affinity IIb, receptor (CD32), Fc-gamma receptor 2B
Protein IDQ8SPW3
Protein Name
Low affinity immunoglobulin gamma Fc region receptor III-A
Scientific Description
Fc gamma RIIB/CD32b proteins exhibit low affinity as complexes or receptors that aggregate the immunoglobulin gammaFc region. ITIM phosphorylated by Fc gamma RIIB/CD32b recruits inositol phosphatases SHIP1 and SHIP2, inhibits Ras activation, down-regulates MAPK activity, reduces PLC-gamma function, and results in PKC activation. Inhibition of MAP kinase pathway and anti-apoptotic kinase Akt inhibit cell proliferation and survival. Fc gamma RIIB/CD32b Protein, Cynomolgus (Biotinylated, HEK293, His-Avi) is the recombinant cynomolgus-derived Fc gamma RIIB/CD32b protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
UNSPSC
41116100
Species
Primate