Fc gamma RIIIA/CD16a, Rat (HEK293, His)

MedChem Express

Fc gamma RIIIA/CD16a, Rat (HEK293, His)

14

Research Use Only

98.0

Fcgr3a

Fc gamma receptor 3A

CD16-2, Fcgr4, low affinity immunoglobulin gamma Fc region receptor III-A, Fc fragment of IgG intermediate affinity IV receptor, Fc fragment of IgG receptor IIIa, Fc fragment of IgG, low affinity IIIa, receptor for (CD16), Fc gamma receptor IIIa, IgG Fc receptor III-A, fcgammaRIV, transmembrane receptor FcgammaRIII-X

Fc gamma RIIIA/CD16a is a receptor for the invariant Fc fragment of immunoglobulin gamma (IgG). Fc gamma RIIIA/CD16a regulates NK cell survival and proliferation and prevents NK cell progenitor cell apoptosis. Fc gamma RIIIA/CD16a plays a role in mediating the anti-tumor activity of therapeutic antibodies by triggering TNFA-dependent ADCC, which promotes the entry of the virus into bone marrow cells during secondary infection and subsequent viral replication through antibody-dependent enhancement (ADE). Fc gamma RIIIA/CD16a Protein, Rat (HEK293, His) is the recombinant rat-derived Fc gamma RIIIA/CD16a, expressed by HEK293, with C-His labeled tag.

-20°C

41116100

Rat