Fc gamma RIIIB/CD16b, Human (NA2, HEK293, His)

MedChem Express

Fc gamma RIIIB/CD16b, Human (NA2, HEK293, His)

10

Research Use Only

95.0

FCGR3B

Fc gamma receptor IIIb

CD16, CD16-I, CD16A, CD16b, FCG3, FCGR3, FCGR3A, FCR-10, FCRIII, FCRIIIb, low affinity immunoglobulin gamma Fc region receptor III-B, Fc fragment of IgG receptor IIIb, Fc fragment of IgG, low affinity IIIb, receptor (CD16b), Fc gamma receptor III-B, Fc-gamma receptor IIIb (CD 16), FcgammaRIIIb, fc-gamma RIII-beta, fc-gamma RIIIb, igG Fc receptor III-1

Low affinity immunoglobulin gamma Fc region receptor III-B

Fc gamma RIIIB/CD16b Protein, a low-affinity receptor for IgG, binds complexed or monomeric IgG. Unlike Fc gamma RIIIA, it cannot mediate antibody-dependent cytotoxicity or phagocytosis. Instead, Fc gamma RIIIB may act as a trap for immune complexes, circulating without activating neutrophils. Existing as a monomer, it interacts with INPP5D/SHIP1, implying its role in intracellular signaling pathways linked to immune responses. Fc gamma RIIIB/CD16b Protein, Human (NA2, HEK293, His) is the recombinant human-derived Fc gamma RIIIB/CD16b protein, expressed by HEK293 , with C-6*His labeled tag.

-20°C

41116100