Fc gamma RIII/CD16, Mouse (HEK293, His)

MedChem Express

Fc gamma RIII/CD16, Mouse (HEK293, His)

10

Research Use Only

98.0

Fcgr3

Fc receptor, IgG, low affinity III

CD16; Fc gamma receptor III; Fcg receptor III; Fcgam; fc-gamma RIII; FcgammaRIII; fcRIII; igG Fc receptor III; low affinity immunoglobulin gamma Fc region receptor III

Low affinity immunoglobulin gamma Fc region receptor III

Fc gamma RIII/CD16 Protein, a low-affinity receptor for IgG1, IgG2a, and IgG2b, is crucial for mediating neutrophil activation in response to IgG complexes. It functions redundantly with Fcgr4 and interacts with INPP5D/SHIP1, emphasizing its involvement in intracellular signaling pathways linked to immune responses. Fc gamma RIII/CD16s significance lies in facilitating cellular activation triggered by immunoglobulin binding. Fc gamma RIII/CD16 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Fc gamma RIII/CD16 protein, expressed by HEK293 , with C-6*His labeled tag.

-80°C

41116100