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Fc (human) IgG1 Control (rec.) (non-lytic)

AG-35B-0016
AdipoGen Life Sciences
ReactivityHuman
Product group Antibodies
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Fc (human) IgG1 Control (rec.) (non-lytic)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Scientific Description
    Negative control in experiments with recombinant proteins fused to Fc (human) IgG1 (non-lytic) (e.g. Prod. No. AG-40B-0230). This protein is not an appropriate negative control for other standard Fc protein constructs. Mutations to the complement (C1q) and FcgR I binding sites of the IgGs Fc fragment render the non-lytic proteins incapable of antibody-directed cytotoxicity (ADCC) and complement-directed cytotoxicity (CDC). - Recombinant Protein. Fc (human) IgG1 (aa 100-330 containing 4 mutations). Source: W2. Lyophilized. Contains PBS. Negative control in experiments with recombinant proteins fused to Fc (human) IgG1 (non-lytic) (e.g. Prod. No. AG-40B-0230). This protein is not an appropriate negative control for other standard Fc protein constructs. Mutations to the complement (C1q) and FcgR I binding sites of the IgGs Fc fragment render the non-lytic proteins incapable of antibody-directed cytotoxicity (ADCC) and complement-directed cytotoxicity (CDC).
  • Reactivity
    Human
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203