Fc (human):Dectin-2 (mouse) (rec.)

AdipoGen Life Sciences

Fc (human):Dectin-2 (mouse) (rec.)

10

Research Use Only

1 mg/ml

>95%

Clec4n

C-type lectin domain family 4, member n

Clec6a, Clecsf10, Nkcl, C-type lectin domain family 6 member A, C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 10, C-type lectin superfamily member 10, DC-associated C-type lectin 2, dectin-2, dendritic cell-associated C-type lectin 2, natural killer complex lectin

C-type lectin domain family 6 member A

Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognizes beta-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif in the cytoplasmic domain, whereas dectin-2 recognizes alpha-mannans and transduces its signal through association with the ITAM-containing Fc receptor gamma-chain. - Protein. Mouse dectin-2 (aa 45-209) is fused at the C-terminus to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: 95% (SDS-PAGE). Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognizes beta-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif in the cytoplasmic domain, whereas dectin-2 recognizes alpha-mannans and transduces its signal through association with the ITAM-containing Fc receptor gamma-chain.

-20°C,2°C to 8°C

41116100

Mouse