Western Blot Positive WB detected in: Hela whole cell lysate, U251 whole cell lysate All lanes: FCHO2 antibody at 3microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 89, 44, 86 kDa Observed band size: 89, 86 kDa
Western Blot Positive WB detected in: Hela whole cell lysate, U251 whole cell lysate All lanes: FCHO2 antibody at 3microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 89, 44, 86 kDa Observed band size: 89, 86 kDa
FCHO2 Antibody
CSB-PA606615LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetFCHO2
Overview
- SupplierCusabio
- Product NameFCHO2 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID115548
- Target nameFCHO2
- Target descriptionFCH and mu domain containing endocytic adaptor 2
- Target synonymsF-BAR domain only protein 2; FCH domain only 2; FCH domain only protein 2
- HostRabbit
- IsotypeIgG
- Protein IDQ0JRZ9
- Protein NameF-BAR domain only protein 2
- Scientific DescriptionFunctions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP-2-dependent endocytosis of the transferin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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