FD1024 [1422456-47-0]

TargetMol Chemicals

FD1024 [1422456-47-0]

16

Chemical

Research Use Only

FD1024

C21H20F2N4O2S

430.47

FD1024 is a potent PIM inhibitor, displaying inhibitory concentrations (IC50s) of 1.96 nM, 38.9 nM, and 4.17 nM for PIM1, PIM2, and PIM3, respectively. It demonstrates significant antiproliferative effects on several AML cell lines, with IC50 values of 0.16 microM for EOL-1, 0.12 microM for MV-4-11, 1.05 microM for KG-1, and 1.39 microM for MOLM-16. Additionally, FD1024 has shown antitumor efficacy in murine models [1].

3 years

-20°C

12352200