Fedratinib (hydrochloride hydrate) (Standard) [1374744-69-0]
HY-10409AR
CAS Number1374744-69-0
Product group Chemicals
Molecular Weight615.62
Overview
- SupplierMedChem Express
- Product NameFedratinib (hydrochloride hydrate) (Standard) [1374744-69-0]
- Delivery Days Customer5
- CAS Number1374744-69-0
- Category SupplierCHEMICAL,detergents_surfactants
- CertificationResearch Use Only
- Molecular Weight615.62
- Scientific DescriptionFedratinib (hydrochloride hydrate) (Standard) is the analytical standard of Fedratinib (hydrochloride hydrate). This product is intended for research and analytical applications. Fedratinib hydrochloride hydrate (TG-101348 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib hydrochloride hydrate shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib hydrochloride hydrate induces cancer cell apoptosis and has the potential for myeloproliferative disorders research[1][2].
- SMILES[H]Cl.[H]O[H].[H]Cl.O=S(C1=CC=CC(NC2=NC(NC3=CC=C(C=C3)OCCN4CCCC4)=NC=C2C)=C1)(NC(C)(C)C)=O
- UNSPSC12352005