FEN1-IN-7 [824983-90-6]

TargetMol Chemicals

FEN1-IN-7 [824983-90-6]

16

Chemical

Research Use Only

FEN1-IN-7

C16H14N2O6S

362.36

FEN1-IN-7 (compound 16), a selective Flap endonuclease-1 (FEN1) inhibitor with an IC50 of 18 nM, plays a role in DNA damage repair in mammalian cells. Additionally, it targets the related endonuclease, xeroderma pigmentosum G (XPG), with an IC50 of 3.04 microM. FEN1-IN-7 enhances the sensitivity of cancer cells to potent DNA alkylating or methylating agents [1].

3 years

-20°C

51202000