Fenbendazole

MedChem Express

Fenbendazole [43210-67-9]

10

43210-67-9

Research Use Only

99.94

C15H13N3O2S

299.35

Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1alpha . Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis . Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 [1] .

O=C(OC)NC1=NC2=CC=C(SC3=CC=CC=C3)C=C2N1

-20°C,2°C to 8°C

12352200