Ferrochelatase antibody [N2C3]
GTX113435
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetFECH
Overview
- SupplierGeneTex
- Product NameFerrochelatase antibody [N2C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.74 mg/ml
- ConjugateUnconjugated
- Gene ID2235
- Target nameFECH
- Target descriptionferrochelatase
- Target synonymsEPP, EPP1, FCE, ferrochelatase, mitochondrial, heme synthase, heme synthetase, protoheme ferro-lyase, protoporphyria, protoporphyrin ferrochelatase
- HostRabbit
- IsotypeIgG
- Protein IDP22830
- Protein NameFerrochelatase, mitochondrial
- Scientific DescriptionThe protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Ast T, Meisel JD, Patra S, et al. Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis. Cell. 2019,177(6):1507-1521.e16. doi: 10.1016/j.cell.2019.03.045Read this paper
- Yang DF, Lee JW, Chen HM, et al. Methotrexate enhances 5-aminolevulinic acid-mediated photodynamic therapy-induced killing of human SCC4 cells by upregulation of coproporphyrinogen oxidase. J Formos Med Assoc. 2014,113(2):88-93. doi: 10.1016/j.jfma.2013.12.005Read this paper





