Fexaramine [574013-66-4]

MedChem Express

Fexaramine [574013-66-4]

10

574013-66-4

Research Use Only

99.24

C32H36N2O3

496.64

Fexaramine is a potent and selective FXR agonist with an EC50 of 25 nM. Fexaramine has no activity against hRXRalpha, hPPARalphagammadelta, mPXR, hPXR, hLXRalpha, hTRbeta, hRARbeta, mCAR, mERRgamma, and hVDR receptors[1][2].

CN(C)C1=CC=C(C2=CC=C(CN(C3=CC(/C=C/C(OC)=O)=CC=C3)C(C4CCCCC4)=O)C=C2)C=C1

-20°C,2°C to 8°C

12352200