ERK and FRS2alpha phosphorylation induced by FGF-21 in bKlotho expressing cells. bKlotho expressing cells were serum starved for 16hr and then stimulated with hFGF-21-His (competitor), FGF-21-Fc (Prod. No. AG-40A-0095), mCD137-Fc (Fc control) and
ERK and FRS2alpha phosphorylation induced by FGF-21 in bKlotho expressing cells. bKlotho expressing cells were serum starved for 16hr and then stimulated with hFGF-21-His (competitor), FGF-21-Fc (Prod. No. AG-40A-0095), mCD137-Fc (Fc control) and
FGF-21 (human):Fc (human) (rec.)
AG-40A-0095
Overview
- SupplierAdipoGen Life Sciences
- Product NameFGF-21 (human):Fc (human) (rec.)
- Delivery Days Customer10
- CertificationResearch Use Only
- Concentration1 mg/ml
- Estimated Purity>95%
- FormulationLiquid
- Protein IDQ9NSA1
- Protein NameFibroblast growth factor 21
- Scientific DescriptionFGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of betaKlotho. - Protein. Human FGF-21 (aa 1-209) is fused at the C-terminus to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: <0.1EU/microg purified protein (LAL test; Lonza). Liquid. 0.2microm-filtered solution in PBS. Purity: >95% (SDS-PAGE). FGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of betaKlotho.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352202