FGF basic/bFGF, Bovine

MedChem Express

FGF basic/bFGF, Bovine

5

Research Use Only

98.0

FGF2

fibroblast growth factor 2

basic fibroblast growth factor; BFGF; FGF-2; fibroblast growth factor 2; fibroblast growth factor 2 (basic); HBGF-2; heparin-binding growth factor 2

Fibroblast growth factor 2

FGF-2 is a member of the fibroblast family involved in bone healing, cartilage repair, bone repair, and nerve regeneration. FGF-2 is also a mitotic promoter that accelerates cell proliferation. FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway. For example, FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration. FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage, respectively[1]. FGF-2 is also a known carcinogen in GBM, which contributes to glioma growth and vascularization[2].FGF basic/bFGF protein, Bovine, consists of 146 amino acids, produced by E.coli with tag free.

-20°C

41116100