FGF8 antibody [8D24]

GeneTex

FGF8 antibody [8D24]

9

WB: 1:500 - 1:1000. IHC-P: 1:20 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking

Research Use Only

Monoclonal

8D24

500 ug/ml

Unconjugated

FGF8

fibroblast growth factor 8

AIGF; androgen-induced growth factor; FGF-8; fibroblast growth factor 8; fibroblast growth factor 8 (androgen-induced); HBGF-8; heparin-binding growth factor 8; HH6; KAL6

Mouse

IgG1

Fibroblast growth factor 8

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203