Bio-Connect

FGFR1OP Polyclonal Antibody

RD75828A
Reddot Biotech
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCEP43
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    FGFR1OP Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.7 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID11116
  • Target name
    CEP43
  • Target description
    centrosomal protein 43
  • Target synonyms
    centrosomal protein 43; FGFR1 oncogene partner; FGFR1OP; fibroblast growth factor receptor 1 oncogene partner; FOP
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohns disease, Graves disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203