FGFR1OP Polyclonal Antibody
RD75828A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCEP43
Overview
- SupplierReddot Biotech
- Product NameFGFR1OP Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.7 mg/ml
- ConjugateUnconjugated
- Gene ID11116
- Target nameCEP43
- Target descriptioncentrosomal protein 43
- Target synonymscentrosomal protein 43; FGFR1 oncogene partner; FGFR1OP; fibroblast growth factor receptor 1 oncogene partner; FOP
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohns disease, Graves disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203