FGFRL1 Polyclonal Antibody
RD75830A
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetFGFRL1
Overview
- SupplierReddot Biotech
- Product NameFGFRL1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.6 mg/ml
- ConjugateUnconjugated
- Gene ID53834
- Target nameFGFRL1
- Target descriptionfibroblast growth factor receptor like 1
- Target synonymsFGF homologous factor receptor; FGF receptor-like protein 1; FGFR5; FGFR-5; FGFR-like protein; FHFR; fibroblast growth factor receptor 5; fibroblast growth factor receptor-like 1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203