FGL1, Mouse (sf9, His)
HY-P75188
Protein IDQ71KU9
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameFGL1, Mouse (sf9, His)
- Delivery Days Customer10
- CertificationResearch Use Only
- Gene ID234199
- Target nameFgl1
- Target descriptionfibrinogen-like protein 1
- Target synonymsfibrinogen-like protein 1; fibrinogen-related protein 1; liver fibrinogen-related protein-1; Mfire1; MFIRE-1; mfrep-1
- Protein IDQ71KU9
- Protein NameFibrinogen-like protein 1
- Scientific DescriptionFGL1 Protein, a potent immune suppressive molecule, inhibits antigen-specific T-cell activation as a major ligand for LAG3. It crucially contributes to LAG3-mediated T-cell inhibitory functions, independently of MHC class II. Secreted by hepatocytes, FGL1 also promotes their growth. The homodimeric form of the protein interacts with LAG3, specifically engaging with its Ig-like domains 1 and 2 through the Fibrinogen C-terminal domain. FGL1 Protein, Mouse (sf9, His) is the recombinant mouse-derived FGL1 protein, expressed by Sf9 insect cells , with C-His labeled tag.
- UNSPSC41116100