FGR antibody [6G2]

GeneTex

FGR antibody [6G2]

9

WB: 1/500 - 1/2000. IHC-P: 1/200 - 1/1000. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

6G2

Unconjugated

FGR

FGR proto-oncogene, Src family tyrosine kinase

SRC2, c-fgr, c-src2, p55-Fgr, p55c-fgr, p58-Fgr, p58c-fgr, tyrosine-protein kinase Fgr, Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, c-fgr protooncogene, c-src-2 proto-oncogene, feline Gardner-Rasheed sarcoma viral oncogene homolog, p55-c-fgr protein, proto-oncogene c-Fgr, proto-oncogene tyrosine-protein kinase FGR, v-fgr feline Gardner-Rasheed sarcoma viral oncogene homolog

Mouse

IgG1

Tyrosine-protein kinase Fgr

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203