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Fibrinogen gamma antibody

GTX108640
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetFGG
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Overview

  • Supplier
    GeneTex
  • Product Name
    Fibrinogen gamma antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.77 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2266
  • Target name
    FGG
  • Target description
    fibrinogen gamma chain
  • Target synonyms
    fibrinogen gamma chain, fibrinogen, gamma polypeptide, testicular tissue protein Li 70
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP02679
  • Protein Name
    Fibrinogen gamma chain
  • Scientific Description
    The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Lai H, Guo Y, Tian L, et al. Protein Panel of Serum-Derived Small Extracellular Vesicles for the Screening and Diagnosis of Epithelial Ovarian Cancer. Cancers (Basel). 2022,14(15). doi: 10.3390/cancers14153719
    Read this paper
  • Matsuno Y, Kusama K, Imakawa K. Characterization of lncRNA functioning in ovine conceptuses and endometria during the peri-implantation period. Biochem Biophys Res Commun. 2022,594:22-30. doi: 10.1016/j.bbrc.2022.01.064
    Read this paper
  • Revollo L, Merrill-Skoloff G, De Ceunynck K, et al. The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation. Blood. 2022,139(1):104-117. doi: 10.1182/blood.2020010342
    Read this paper
  • Seto S, Morimoto K, Yoshida T, et al. Proteomic Profiling Reveals the Architecture of Granulomatous Lesions Caused by Tuberculosis and Mycobacterium avium Complex Lung Disease. Front Microbiol. 2019,10:3081. doi: 10.3389/fmicb.2019.03081
    Read this paper
  • Rottmar M, Müller E, Guimond-Lischer S, et al. Assessing the osteogenic potential of zirconia and titanium surfaces with an advanced in vitro model. Dent Mater. 2019,35(1):74-86. doi: 10.1016/j.dental.2018.10.008
    Read this paper
  • Chuang YC, Lei HY, Lin YS, et al. Dengue virus-induced autoantibodies bind to plasminogen and enhance its activation. J Immunol. 2011,187(12):6483-90. doi: 10.4049/jimmunol.1102218
    Read this paper

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