Fibromodulin antibody

GeneTex

Fibromodulin antibody

7

WB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

FMOD

fibromodulin

FM, SLRR2E, fibromodulin, KSPG fibromodulin, collagen-binding 59 kDa protein, epididymis secretory sperm binding protein, keratan sulfate proteoglycan fibromodulin

Rabbit

IgG

Fibromodulin

Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

-20°C or -80°C,2°C to 8°C

12352203