Fidrisertib [2141955-96-4]

MedChem Express

Fidrisertib [2141955-96-4]

5

2141955-96-4

Research Use Only

98.17

C31H42N6O4

562.70

Fidrisertib (BLU-782) is the orally active inhibitor for activin receptor-like kinase 2 (ALK2) that inhibits ALK2R206H, ALK2, ALK1, ALK6, ALK3, ALK4, TGFbetaR2 and ALK5 with IC50s of 0.2, 0.6, 3, 24, 45, 65, 67 and 155 nM, respectively[1][2].

O=C(N1CCN(C2=CC=NN3C2=CC(C4=NC=C(C5(OCC)CCN(C(C)C)CC5)C=C4)=C3)CC1)O[C@H]6COCC6

-20°C,2°C to 8°C

12352200