FIIN-1

MedChem Express

FIIN-1 [1256152-35-8]

10

1256152-35-8

Research Use Only

99.11

C32H39Cl2N7O4

656.60

FIIN-1 is a potent, irreversible, selective FGFR inhibitor. FIIN-1 binds to FGFR1/2/3/4 and Flt1/4 with K d s of 2.8/6.9/5.4/120 nM and 32/120 nM respectively. The biochemical IC 50 s of FIIN-1 are 9.2, 6.2, 11.9, and 189 nM against FGFR1/2/3/4, respectively [1] .

C=CC(NC1=CC=CC(CN(C2=NC(NCCCCN(CC)CC)=NC=C2CN3C4=C(Cl)C(OC)=CC(OC)=C4Cl)C3=O)=C1)=O

-20°C,2°C to 8°C

12352200