FIIN-3

AbMole BioScience

FIIN-3

9

1637735-84-2

Research Use Only

C34H36Cl2N8O4

691.61

FIIN-3 is a potent, selective, irreversible and the next-generation covalent FGFR inhibitor with IC50 values of 13.1, 21, 31.4 and 35.3 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.

COC1=CC(=C(Cl)C(=C1Cl)NC(=O)N(CC2=CC=C(NC(=O)C=C)C=C2)C3=NC=NC(=C3)NC4=CC=C(C=C4)N5CCN(C)CC5)OC

12352200