Filamin A antibody [N2], N-term

GeneTex

Filamin A antibody [N2], N-term

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

FLNA

filamin A

ABP-280; ABPX; actin binding protein 280; alpha-filamin; CSBS; CVD1; endothelial actin-binding protein; epididymis secretory sperm binding protein; FGS2; filamin A, alpha; filamin-1; filamin-A; FLN; FLN1; FLN-A; FMD; MNS; NHBP; non-muscle filamin; OPD; OPD1; OPD2; XLVD; XMVD

Rabbit

IgG

Filamin-A

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

-20°C or -80°C,2°C to 8°C

12352203