Filanesib (hydrochloride)

MedChem Express

Filanesib (hydrochloride) [1385020-40-5]

14

1385020-40-5

Research Use Only

C20H23ClF2N4O2S

456.94

Filanesib (ARRY-520) hydrochloride is a selective and noncompetitive kinesin spindle protein (KSP) inhibitor, with an IC50 of 6 nM for human KSP. Filanesib induces cell death by apoptosis in vitro. Filanesib has potent anti-proliferative activity[1][2][3].

O=C(N1[C@@](C2=CC=CC=C2)(CCCN)SC(C3=CC(F)=CC=C3F)=N1)N(OC)C.[H]Cl

12352200