Filastatin [431996-53-1]

MedChem Express

Filastatin [431996-53-1]

5

431996-53-1

Research Use Only

99.27

C18H18ClN3O3

359.81

Filastatin is a long-lasting inhibitor of Candida albicans filamentation. Filastatin inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 microM in the GFP-based adhesion assay. Filastatin inhibits fungal adhesion to polystyrene and human cells, the yeast-to-hyphal morphological transition, induction of the hyphal-specific HWP1 promoter. Filastatin has potent antifungal effect[1].

O=C(C1=CC=C(C)C(Cl)=C1)N2CCN(C3=CC=C([N+]([O-])=O)C=C3)CC2

-20°C,2°C to 8°C

12352200