FIP200 antibody
GTX129093
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetRB1CC1
Overview
- SupplierGeneTex
- Product NameFIP200 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9821
- Target nameRB1CC1
- Target descriptionRB1 inducible coiled-coil 1
- Target synonyms200 kDa FAK family kinase-interacting protein; ATG17; CC1; FAK family kinase-interacting protein of 200 kDa; FIP200; phosphatase 1, regulatory subunit 131; PPP1R131; RB1-inducible coiled-coil protein 1
- HostRabbit
- IsotypeIgG
- Protein IDQ8TDY2
- Protein NameRB1-inducible coiled-coil protein 1
- Scientific DescriptionThe protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity. Gao Y et al., 2022 Dec, Cell ResRead more
- MicroRNA-20a-mediated loss of autophagy contributes to breast tumorigenesis by promoting genomic damage and instability. Liu L et al., 2017 Oct 19, OncogeneRead more