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FIP200 antibody

Name: FIP200 antibody
SKU: GTX129093_G10
Availability: BackOrder

GTX129093

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetRB1CC1

Overview

Supplier
GeneTex
Product Name
FIP200 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID9821
Target name
RB1CC1
Target description
RB1 inducible coiled-coil 1
Target synonyms
ATG17, CC1, FIP200, PPP1R131, RB1-inducible coiled-coil protein 1, 200 kDa FAK family kinase-interacting protein, FAK family kinase-interacting protein of 200 kDa, phosphatase 1, regulatory subunit 131
Host
Rabbit
Isotype
IgG
Protein IDQ8TDY2
Protein Name
RB1-inducible coiled-coil protein 1
Scientific Description
The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Gao Y, Zheng X, Chang B, et al. Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity. Cell Res. 2022,32(12):1086-1104. doi: 10.1038/s41422-022-00731-w
Read this paper
Liu L, He J, Wei X, et al. MicroRNA-20a-mediated loss of autophagy contributes to breast tumorigenesis by promoting genomic damage and instability. Oncogene. 2017,36(42):5874-5884. doi: 10.1038/onc.2017.193
Read this paper