Firazorexton hydrate [2861934-86-1]

TargetMol Chemicals

Firazorexton hydrate [2861934-86-1]

16

Chemical

Firazorexton hydrate

C22H25F3N2O4S.3/2H2O

497.53

Firazorexton hydrate (TAK-994) is a brain-penetrant, orally active agonist of the orexin type 2 receptor (OX2R) with a potent EC50 of 19 nM, effectively reducing wakefulness fragmentation and cataplexy-like episodes in mouse models of narcolepsy [1].

3 years

C([C@@H]1N(C(C(C)(C)O)=O)CC[C@@H]1NS(C)(=O)=O)C2=C(F)C(=CC=C2)C3=CC(F)=CC(F)=C3.O

-20°C

12352200