Fisogatinib

MedChem Express

Fisogatinib [1707289-21-1]

5

1707289-21-1

99.87

C24H24Cl2N4O4

503.38

Fisogatinib (BLU-554) is a potent, highly selective and orally active fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC 50 of 5 nM. Fisogatinib has significant anti-tumor activity in models of hepatocellular carcinoma (HCC) that are dependent on FGFR4 signalling [1] [2] .

C=CC(N[C@@H]1[C@H](NC2=NC=C3C=C(C4=C(Cl)C(OC)=CC(OC)=C4Cl)C=CC3=N2)COCC1)=O

-20°C,2°C to 8°C

12352200