FIT-039

MedChem Express

FIT-039 [1113044-49-7]

10

1113044-49-7

Research Use Only

99.56

C17H18FN3S

315.41

FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC50 of 5.8 microM for CKD9/cyclin T1. FIT-039 does not inhibit other CDKs and other kinases. FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 microM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses.

FC1=CC(NC(C2=CC=NC=C2)=S)=C(N3CCCCC3)C=C1

-20°C

12352200