FITC Anti-Human CD49d Antibody

Reddot Biotech

FITC Anti-Human CD49d Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

BU49

FITC

ITGA4

integrin subunit alpha 4

CD49D, IA4, integrin alpha-4, 269C wild type, CD49 antigen-like family member D, VLA-4 subunit alpha, alpha 4 subunit of VLA-4 receptor, antigen CD49D, alpha-4 subunit of VLA-4 receptor, integrin alpha-IV, very late activation protein 4 receptor, alpha 4 subunit

Mouse

IgG1

Integrin alpha-4

CD49d is a 150 kD alpha integrin chain known as alpha4 integrin or VLA-4 alpha chain. It forms a heterodimer with either integrin beta1 (alpha4beta1, VLA-4) or beta7 (alpha4beta7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. alpha4beta7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells. - This is a FITC Anti-Human CD49d Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Human

2°C to 8°C

41116161