FITC Anti-Mouse FcOemicroRIOe+/- Antibody

Reddot Biotech

FITC Anti-Mouse FcOemicroRIOe+/- Antibody

5

44986

0.5 mg/ml

Fcer1a

Fc receptor, IgE, high affinity I, alpha polypeptide

FcE; Fce1; Fce1a; fc-epsilon RI-alpha; fcepsilonri; FcERI; Fcr-; Fcr-5; high affinity immunoglobulin epsilon receptor subunit alpha; igE Fc receptor subunit alpha

FcOemicroRIOe+/- is a transmembrane protein belonging to the Ig superfamily. FcOemicroRIOe+/- forms a tetrameric complex with one beta and two Oe≥-subunits. The FcOemicroRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcOemicroRIOe+/-, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcOemicroRIOe+/- subunit.

2°C to 8°C

12352203