FITC-Labeled EGFR, Human (621a.a, HEK293, His)
HY-P704574
Protein IDP00533
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameFITC-Labeled EGFR, Human (621a.a, HEK293, His)
- Delivery Days Customer999
- CertificationResearch Use Only
- Gene ID1956
- Target nameEGFR
- Target descriptionepidermal growth factor receptor
- Target synonymsERBB, ERBB1, ERRP, HER1, NISBD2, NNCIS, PIG61, mENA, epidermal growth factor receptor, EGFR vIII, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, epidermal growth factor receptor tyrosine kinase domain, erb-b2 receptor tyrosine kinase 1, proto-oncogene c-ErbB-1, receptor tyrosine-protein kinase erbB-1
- Protein IDP00533
- Protein NameEpidermal growth factor receptor
- Scientific DescriptionThe EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. FITC-Labeled EGFR Protein, Human (621a.a, HEK293, His) is the recombinant human-derived FITC-Labeled EGFR protein, expressed by HEK293, with C-His labeled tag.
- UNSPSC41116100
- SpeciesHuman