FK-506 (Tacrolimus)

Biorbyt

FK-506 (Tacrolimus)

16

104987-11-3

Research Use Only

C44H69NO12

804.0182

Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties.

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