
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA008702LA01HU at dilution of 1:100
FKBP6 Antibody
CSB-PA008702LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetFKBP6
Overview
- SupplierCusabio
- Product NameFKBP6 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8468
- Target nameFKBP6
- Target descriptionFKBP prolyl isomerase family member 6 (inactive)
- Target synonyms36 kDa FKBP; FK506 binding protein 6, 36kDa; FK506-binding protein 6; FKBP prolyl isomerase 6; FKBP36; immunophilin FKBP36; inactive peptidyl-prolyl cis-trans isomerase FKBP6; inactive PPIase FKBP6; peptidyl-prolyl cis-trans isomerase FKBP6; PPIase FKBP6; rotamase
- HostRabbit
- IsotypeIgG
- Protein IDO75344
- Protein NameInactive peptidyl-prolyl cis-trans isomerase FKBP6
- Scientific DescriptionCo-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161