FKBP6 Antibody

Cusabio

FKBP6 Antibody

20

ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

FKBP6

FKBP prolyl isomerase family member 6 (inactive)

36 kDa FKBP; FK506 binding protein 6, 36kDa; FK506-binding protein 6; FKBP prolyl isomerase 6; FKBP36; immunophilin FKBP36; inactive peptidyl-prolyl cis-trans isomerase FKBP6; inactive PPIase FKBP6; peptidyl-prolyl cis-trans isomerase FKBP6; PPIase FKBP6; rotamase

Rabbit

IgG

Inactive peptidyl-prolyl cis-trans isomerase FKBP6

Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.

Human

-20°C or -80°C

41116161