FKBP8 Antibody, Biotin conjugated

Cusabio

FKBP8 Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

FKBP8

FKBP prolyl isomerase 8

FKBP38, FKBPr38, peptidyl-prolyl cis-trans isomerase FKBP8, 38 kDa FK506-binding protein, 38 kDa FKBP, FK506 binding protein 8, 38kDa, FK506-binding protein 8, FKBP-38, FKBP-8, PPIase FKBP8, hFKBP38, rotamase

Rabbit

IgG

Peptidyl-prolyl cis-trans isomerase FKBP8

Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.

Human

-20°C or -80°C

41116161