Flavokawain A [3420-72-2]

TargetMol Chemicals

Flavokawain A [3420-72-2]

9

3420-72-2

Research Use Only

Flavokawain A

99.72%

C18H18O5

314.33

NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significantly reduce the expression of CDK1-inhibitory kinases, Myt1 and Wee1, and cause cyclin B1 protein accumulation leading to CDK1 activation in T24 cells. 3. Flavokawain A (Flavokavain A) may exert anti-inflammatory responses by suppressing LPS-induced expression of pro-inflammatory mediators via blockage of NF-kappaB-AP-1-JNK/p38 MAPK signaling pathways in the murine macrophages.

3 years

COc1ccc(\C=C\C(=O)c2c(O)cc(OC)cc2OC)cc1

-20°C

12352200