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Flavopiridol [146426-40-6]

Flavopiridol [146426-40-6]

T6837
TargetMol Chemicals
CAS Number146426-40-6
Product group Chemicals
Estimated Purity99.85%
Molecular Weight401.84
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Flavopiridol [146426-40-6]
  • Delivery Days Customer
    4
  • CAS Number
    146426-40-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Flavopiridol
  • Estimated Purity
    99.85%
  • Molecular Formula
    C21H20ClNO5
  • Molecular Weight
    401.84
  • Scientific Description
    Flavopiridol (Alvocidib) (Alvocidib) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1, 2, 4, 6 versus CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Phase 1/2.
  • Shelf life instruction
    3 years
  • SMILES
    CN1CC[C@@H]([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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