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Flavopiridol hydrochloride

M3483
AbMole BioScience
CAS Number131740-09-5
Product group Chemicals
Molecular Weight438.3
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Flavopiridol hydrochloride
  • Delivery Days Customer
    9
  • CAS Number
    131740-09-5
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C21H20ClNO5.HCl
  • Molecular Weight
    438.3
  • Scientific Description
    Flavopiridol competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA.
  • SMILES
    Cl.CN1CCC(C(O)C1)C2=C3OC(=CC(=O)C3=C(O)C=C2O)C4=C(Cl)C=CC=C4
  • UNSPSC
    12352200

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