FLIP peptide

GeneTex

FLIP peptide

9

The peptide is used for blocking the activity of FLIPs (GTX28423). Incubatingthe peptide with equal volume of antibody for 30 min at 37C usually completely blocks theantibody activity in Western blotting.

Neutralisation/Blocking

Research Use Only

0.20 mg/ml

Unconjugated

The human homolog of viral FLIP has four splice variants known as FLIP alpha, Beta, gamma and kappa. These are FLICE inhibitory proteins also known as Casper, I-FLICE, FLAME-1, CASH, CLARP and Usurpin. They contain two death effector domains and one caspase domain. FLIP interacts with FADD, caspase-8 and 10 to inhibit apoptosis initiated by Fas, TNF-R1 and TRAIL-R.

-20°C

12352202