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ProductsBack/FLNA Polyclonal Antibody

Immunohistochemistry of paraffin-embedded Human colon muscle using FLNA Polyclonal Antibody at dilution of 1:100 (40x lens).

Immunohistochemistry of paraffin-embedded Human colon muscle using FLNA Polyclonal Antibody at dilution of 1:100 (40x lens).

Immunohistochemistry of paraffin-embedded Human colon muscle using FLNA Polyclonal Antibody at dilution of 1:100 (40x lens).

FLNA Polyclonal Antibody

E-AB-62082

Product group Antibodies

Overview

Supplier
Elabscience
Product Name
FLNA Polyclonal Antibody
Delivery Days Customer
12
Certification
Research Use Only
Scientific Description
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
UNSPSC
12352203